Case discussion The patient is suffering from multiple myeloma. Multiple myelomas represent a malignant proliferation of plasma cells derived from a single clone. The plasma cells in a normal individual are end-stage cells that secrete specific antibodies for a few days and then die. In contrast, the plasma cells in an individual with multiple myeloma […]
Image challenge-1- Answer Read More »
A 22-year-old man collapsed from dehydration during maneuvers in the desert and was sent to an emergency. A high level of glucose was observed in his urine. He was suspected of being a diabetic. Further tests, however, determined that his serum insulin level was normal. A glucose tolerance test exhibited a normal pattern; further testing
Clinical significance of SGLT-2 Read More »
A 23-year-old bodybuilder visits his physician with complaints of fatigue, depression, insomnia, hair loss, and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency given the patients’ diet and symptoms. Which
Answer to the Question of the week -1 Read More »
Q.1- A 73-year-old woman is transferred to an intensive care unit after she is found to be in septic shock. It is believed that she originally had a urinary tract infection and that the bacteria seeded her bloodstream. The critical care fellow is concerned she may not have an adequate stress response in this situation.
Practice questions Read More »
1)- Several complexes in the electron transport chain contain non-heme iron. The iron in these complexes is bound tightly to which of the following amino acids? a) Serine b) Tyrosine c) Cysteine d) Methionine e) Glutamine 2)- A 27 –year-old female with epilepsy has been taking Phenytoin to control her seizures. She is pregnant and
Practice Questions Read More »
S.N. Process/Pathway affected Disease Major Manifestation 1) Digestion Lactose intolerance Sucrase/Isomaltase deficiency Inability to digest dairy products, bloating, pain- abdomen, diarrhea or constipation, etc. 2) Absorption (SGLT-1or SGLT-2 deficiency) Glucose/Galactose malabsorption Impaired dietary glucose/galactose absorption (SGLT-1), or Renal glycosuria (SGLT-2) 3) Glycolysis Hexokinase or Pyruvate kinase deficiency ( Hemolytic anemia 4) PDH Complex
Metabolic disorders- Carbohydrate metabolism Read More »
A 56-year-old man with long-standing poorly controlled diabetes mellitus visits his primary care physician for a follow up after recent hospitalization. The patient experienced an episode of acute renal failure while in the hospital and his creatinine level rose to 4 mg/dl. Creatinine, a marker of renal function is produced from which of the following
Biologically important peptides Read More »
A novel (new) coronavirus is causing an outbreak of respiratory illness that began in the city of Wuhan, Hubei Province, China. This outbreak began in early December 2019 and continues to grow. Initially, some patients were linked to the Wuhan South China Seafood City (also called the South China Seafood Wholesale Market and the Hua
Novel Coronavirus from China Read More »
Case details A severe form of obstructive lung disease starting with dyspnea and leading progressively towards emphysema was found in several members of the family. One brother had died earlier of lung disease. Blood plasma from his surviving brother and sister showed an abnormally low concentration of α1-Antitrypsin (5.5 μm, normal is 20–48 μm), the
α1-Antitrypsin deficiency- a case study (week 1) Read More »
A 23-year-old bodybuilder visits his physician with complaints of fatigue, depression, insomnia, hair loss, and dry skin. He tells the physician he has been “bulking up” for an upcoming competition, and his meals consist mostly of eight raw eggs along with low-fat milk. The physician suspects biotin deficiency given the patients’ diet and symptoms. Which
Question of the week 1 Read More »
