February 2020

Elevated Acyl carnitine compounds and associated hypoglycemia- What is the defect?

Case details  A 5- year-old boy suffered gastroenteritis for two days and was brought to the emergency in the semiconscious state. Blood glucose at the time of admission was 45 mg/dl and his urine was negative for glucose and ketone bodies. Glucose was administered intravenously and his condition improved within 10 minutes. Subsequent laboratory investigations […]

Elevated Acyl carnitine compounds and associated hypoglycemia- What is the defect? Read More »

Impaired TCA cycle enzyme activity in angular stomatitis

A postoperative patient on intravenous fluids develops lesions in the mouth (angular stomatitis). Urinalysis indicates an excretion of 15 μg riboflavin/mg creatinine, which is abnormally low. Which of the following TCA cycle enzymes is most likely to be affected? Citrate synthase Isocitrate dehydrogenase Fumarase Malate dehydrogenase Succinate dehydrogenase Details- E) – Succinate dehydrogenase is the

Impaired TCA cycle enzyme activity in angular stomatitis Read More »

error: Content is protected !!