USMLE styled question bank

Amino Acid Metabolism- Set 2- Multiple Choice Questions

Q.1 – A 12-year-old boy develops convulsions. After an Electroencephalogram (EEG), a neurologist determines that the child has epilepsy. He is started on benzodiazepine, which promotes the activity of GABA. GABA is derived from Glutamate by which of the following reactions? A) Deamination B) Decarboxylation C) Dehydrogenation D) Hydroxylation E) Transamination Answer: B) Decarboxylation Explanation: […]

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Amino acid Metabolism- Multiple-Choice Questions- Set 1

Q.1 – Which of the following is a common compound shared by the TCA and Urea cycles? A) α-Ketoglutarate B) Succinyl-CoA C) Oxaloacetate D) Fumarate Answer: D) Fumarate Explanation: Fumarate is a common compound in both the TCA (Tricarboxylic Acid) and urea cycles. In the TCA cycle, fumarate is formed from succinate by the enzyme

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Enzymology Revision (Multiple Choice Questions With Complete Explanations)

Q.1: Glycogen phosphorylase, which mobilizes glycogen for energy, requires which of the following as a cofactor? Adenosyl Cobalamine Coenzyme A Pyridoxal phosphate Tetrahydrofolate Thiamine pyrophosphate Correct Answer: C) Pyridoxal phosphate Explanation: Glycogen phosphorylase is instrumental in the process of glycogenolysis, where it facilitates the breakdown of glycogen into glucose-1-phosphate, thereby playing a vital role in

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Biochemistry-Practice Questions (Problem-based multiple choice questions)

Biochemistry-Practice Questions (Problem-based multiple choice questions) 1)- Several complexes in the electron transport chain contain non-heme iron. The iron in these complexes is bound tightly to which of the following amino acids? a) Serine b) Tyrosine c) Cysteine d) Methionine e) Glutamine 2)- A 27 –year-old female with epilepsy has been taking Phenytoin to control

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Nonessential in normal health but essential amino acid under conditions of enhanced growth or surgical recovery

Case details An 8-year-old child requires surgical intervention and substantial recovery time in the hospital. Therefore, a nutritionist recommends a specific dietary plan. The plan includes a protein-rich diet with the special supplementation of an amino acid that is typically considered nonessential but becomes an essential amino acid under enhanced growth or surgical recovery conditions.

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ATP- The energy currency within the cell

Q.- Adenosine triphosphate (ATP) is the energy currency within the cell. Which of the following best describes the type of compound ATP is? A. Phospholipid B. Amino acid C. Nucleotide D. Triacylglycerol E. Oligosaccharide. Details The correct answer is -C- Nucleotide. The nucleotide coenzyme adenosine triphosphate (ATP) is the most important form of chemical energy

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Elevated Acyl carnitine compounds and associated hypoglycemia- What is the defect?

Case details  A 5- year-old boy suffered gastroenteritis for two days and was brought to the emergency in the semiconscious state. Blood glucose at the time of admission was 45 mg/dl and his urine was negative for glucose and ketone bodies. Glucose was administered intravenously and his condition improved within 10 minutes. Subsequent laboratory investigations

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Impaired TCA cycle enzyme activity in angular stomatitis

A postoperative patient on intravenous fluids develops lesions in the mouth (angular stomatitis). Urinalysis indicates an excretion of 15 μg riboflavin/mg creatinine, which is abnormally low. Which of the following TCA cycle enzymes is most likely to be affected? Citrate synthase Isocitrate dehydrogenase Fumarase Malate dehydrogenase Succinate dehydrogenase Details- E) – Succinate dehydrogenase is the

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