Oxidative phosphorylation

Case study- Luft syndrome (Hypermetabolic mitochondrial syndrome)

Case Study A 30 -year- old patient reported to medical OPD complaining of generalized weakness, excessive perspiration, and high caloric intake without an increase in body weight. From the age of seven, she had suffered from profuse sweating that forced her to change clothes about ten times a day. To compensate for the loss of

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Electron Transport Chain -strictly aerobic (a brief review)

Introduction Most of the energy liberated during the oxidation of carbohydrates, fatty acids, and amino acids are made available within mitochondria as reducing equivalents (—H or electrons). The NADH and FADH2 formed in glycolysis, fatty acid oxidation, and the citric acid cycle are energy-rich molecules because each contains a pair of electrons having a high

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Non-shivering thermogenesis : uncoupling of oxidative phosphorylation

Which of the following occurs in non-shivering thermogenesis? A) Glucose is oxidized to lactate B) Fatty acids uncouple oxidative phosphorylation C) ATP is spent on heat production D) Glycogen is excessively degraded E) Fatty acids are excessively oxidized The correct answer is C- Fatty acids uncouple oxidative phosphorylation Basic Concept The reduction of molecular oxygen

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Reduced state of the respiratory chain carriers (Inhibition of electron transport chain)

As electrons are received and passed down the transport chain, the electron carriers are first reduced with the acceptance of the electron and then oxidized with loss of the electron. A patient poisoned by which of the following compounds has the most highly reduced state of most of the respiratory chain carriers? A. Antimycin A

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