Disorders of lipid metabolism-part 2
Disorders of lipid metabolism-part 2 Read More »
Enzyme and pathway Effect of substrate concentration Allosteric Modification/ Feedback Inhibition/Covalent modification Induction/ Repression Clinical Significance Acetyl co A Carboxylase (Fatty acid synthesis) Activity increases during the well-fed state Activity decreases during fasting Activator- Citrate, ATP Acetyl co A Insulin- activates the enzyme by covalent modification of the enzyme (dephosphorylation through stimulating protein phosphatase enzyme) Inhibitors–
Regulatory Mechanisms- Lipid Metabolism (summary Chart) Read More »
Fatty acid metabolism- Animations http://www.wiley.com/legacy/college/boyer/0470003790/animations/fatty_acid_metabolism/fatty_acid_metabolism.htm http://www.brookscole.com/chemistry_d/templates/student_resources/shared_resources/animations/carnitine/carnitine1.html http://nutrition.jbpub.com/resources/animations.cfm?id=23&debug=0 Cholesterol metabolism- Animations http://www.google.mu/url?sa=t&rct=j&q=cholesterol%20metabolism&source=web&cd=6&ved=0CEgQFjAF&url=http%3A%2F%2Fwww.wiley.com%2Fcollege%2Fboyer%2F0470003790%2Fanimations%2Fcholesterol%2Fcholesterol.htm&ei=Y1u_To6eLpS3hAfBl5yqBA&usg=AFQjCNEnz6PRIRPbutRUAAO5FS-aqAxguQ&cad=rja Lipoprotein metabolism http://www.wiley.com/college/pratt/0471393878/student/animations/lipoproteins/index.html https://www.youtube.com/watch?v=97uiV4RiSAY Atherosclerosis https://www.youtube.com/watch?v=OHE1ig4k64M LDL and HDL cholesterol https://www.youtube.com/watch?v=0U7YHRW5dyc
Lipid metabolism- animations Read More »
Introduction Renal clearance is a measurement to analyze the functions of the kidney. By definition, clearance is the volume of plasma from which the excretion completely removes a substance through the kidney in a given amount of time (usually a minute). For example, the clearance for urea is 75 ml/min. This means that the kidney
Renal clearance- a quick revision Read More »
ATP SYNTHASE ANIMATIONS Click the link below for more animations http://www.wiley.com/college/pratt/0471393878/student/animations/oxidative_phosphorylation/index.html
Animations – ATP synthase complex and electron transport chain Read More »
S.N. Process/Pathway affected Disease Major Manifestation 1) Digestion Lactose intolerance Sucrase/Isomaltase deficiency Inability to digest dairy products, bloating, pain- abdomen, diarrhea or constipation, etc. 2) Absorption (SGLT-1or SGLT-2 deficiency) Glucose/Galactose malabsorption Impaired dietary glucose/galactose absorption (SGLT-1), or Renal glycosuria (SGLT-2) 3) Glycolysis Hexokinase or Pyruvate kinase deficiency ( Hemolytic anemia 4) PDH Complex
Metabolic disorders- Carbohydrate metabolism Read More »
A 56-year-old man with long-standing poorly controlled diabetes mellitus visits his primary care physician for a follow up after recent hospitalization. The patient experienced an episode of acute renal failure while in the hospital and his creatinine level rose to 4 mg/dl. Creatinine, a marker of renal function is produced from which of the following
Biologically important peptides Read More »